PCORnet Bariatric Study
PaTH Protocol PI(s):
Purpose: The use of bariatric surgery as a treatment for severe obesity has increased dramatically over the past two decades, but there have been few high-quality, long-term studies comparing the outcomes of different procedures.
Goal(s): The main goal of the proposed study is to provide accurate estimates of the one-, three-, and five-year benefits and risks of the three most common bariatric procedures—Roux-en-y gastric bypass, adjustable gastric banding, and sleeve gastrectomy—with a focus on outcomes that are important to adults and adolescents with severe obesity. These include, (a) changes in weight; (b) remission and relapse of diabetes; and (c) risk of major adverse events.
Study Design: Obesity Observational Research Initiative
The study will involve 10 of PCORnet’s Clinical Data Research Networks (CDRNs) including 53 healthcare organizations and more than 60,000 bariatric patients, with 50 percent gastric bypass, 10 percent gastric banding, and 40 percent sleeve gastrectomy procedures. This study will also include more than 900 adolescent bariatric patients (the largest adolescent cohort ever) and more than 17,000 patients with diabetes.
PCORnet Partners /CDRN Participating Sites:
Coordinating Center: Group Health Cooperative